http://www.merck.com/product/patent/home.html. Copyright 1995-2023 Merck & Co., Inc., Rahway, NJ, USA and its affiliates. Safe-Guard AquaSol was administered orally as medicated drinking water to a group of 110 breeding chickens (10 male and 100 female) at 3 mg fenbendazole/kg body weight/day (3 times the recommended label dose) for 21 consecutive days (4 times the recommended duration). Consult your Veterinarian for assistance in the diagnosis, treatment, and control of parasitism. ****Oral/Water Soluble Vaccines for Swine, ***Products for Farrowing and Breeding Swine, ***Swine Ear Tags, Marking, & Identification Products. [Note: If the total volume of the 1 to 1 dilution needed exceeds the volume of the largest available measuring device, divide the total volume into two or more smaller batches of 1 to 1dilution, prepared following the steps below. Stir until the content in the stock suspension tank is visibly homogeneous. For Patent Information: http://www.merck.com/product/patent/home.html. In this case, you would have to deworm your older chickens first before deworming the baby chicks. These studies supported the safety of Safe-Guard AquaSol in broiler chickens, replacement chickens, laying hens and breeding chickens when administered in drinking water at 1 mg fenbendazole/kg body weight/day for 5 consecutive days. When put into water, each one will settle out because they are suspensions (suspended for a time in water.) The medicated water should appear hazy. At the end of the treatment phase, gross necropsies were performed on 48 chickens from each group, and organs weights were evaluated. Barrow and gilt breeds representative of U.S. commercial production were used. This thread also discusses dosing to avoid withdrawl, I've never done it this way (because I want to know for sure each bird got the correct dose), but here it is if you want to consider it: Hello again! For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS, or http://www.fda.gov/AnimalVeterinary/SafetyHealth. 8713184147011. Fifteen chickens were necropsied before treatment initiation, and 15 chickens were necropsied seven days after treatment for worm counts. These studies supported the safety of Safe-Guard AquaSol in broiler chickens, replacement chickens, laying hens and breeding chickens when administered in drinking water at 1 mg fenbendazole/kg body weight/day for 5 consecutive days. Accidental ingestion may cause gastrointestinal disturbances and hypersensitivity reactions in humans. Our mission is to manufacture and supply products and give support to our animal agriculture customers helping them do the best possible job of caring for their animals at the most reasonable cost. Safe-Guard Aquasol for Chickens & Swine Indications, Warnings and cautions for Safe-Guard Aquasol for Chickens & Swine, Direction and dosage information for Safe-Guard Aquasol for Chickens & Swine. Safe-Guard AquaSol must be administered orally to chickens via the drinking water at a dailydose of 1.0 mg/kg BW (0.454 mg/lb) for 5 consecutive days. A decrease of effectiveness over time may indicate the development of resistance to the dewormer administered. Safeguard is usually administered orally, I do it with an oral syringe. No clinically significant effects related to the administration of Safe-Guard AquaSol were observed for any of the parameters evaluated. All rights reserved. Safe-Guard can be purchased over-the-counter. Adequacy of infection was demonstrated at both study sites by having more than 6 non-medicated pigs (11 of the 12 non-medicated animals in MN and 9 of the 12 non-medicated animals in CA) with adult T. suis worm counts of 100 or more per animal. OTHER WARNINGS: Parasite resistance may develop to any dewormer. Hematology and clinical chemistry parameters were evaluated in 24 chickens from each group. Another group of 120 chickens (60 male and 60 female) was provided non-medicated drinking water and used as a control group. DESCRIPTION: Safe-Guard AquaSol is a suspension concentrate containing fenbendazole, an antiparasitic. These two pigs had exhibited abnormal fecal consistency prior to treatment with FBZ. Safe-Guard AquaSol must be administered orally to chickens via the drinking water at a daily dose of 1 mg/kg BW (0.454 mg/lb) for 5 consecutive days. Yes the dosage is 0.25 ml (1/4 ml) per pound given orally for 5 consecutive days. Safe-Guard is safe for use with chickens. Only two pigs at the Minnesota (MN) site that were treated with FBZ had abnormal post-treatment observations ("loose stools"). The margin of safety in broiler chickens was conducted in 480 broiler chickens. Safe-Guard AquaSol for Chickens Indications. A fourth field effectiveness study was conducted in the US using 550 Cobb breed breeder hens (63 weeks old). Update of Safe Guard Withdrawal Period, Yogurt Use in Chickens, & More, Yet another (Canada based) de-worming thread! Updated: 2023-02-28. Zyfend A, 30 mL. Ensure that the total amount of medicated water offered is consumed. The two pigs with the two lowest FEC counts within a weight block were randomized one per treatment group and the two pigs with the highest FEC counts within a weight block were randomized one per treatment group. The following formula should be used to estimate the dose: Total estimated body weight of the chickens in kilograms x 0.005 mL = amount of Safe-Guard Aquasol to use in milliliters in a day. Add the entire 1 to 1 dilution of Safe-Guard AquaSol in water to the medication tank containing the volume of drinking water usually consumed by the animals in 3 to 24 hours. Once opened, do not store the container above 25 C(77F). Save my name, email, and website in this browser for the next time I comment. Accidental ingestion may cause gastrointestinal disturbances and hypersensitivity reactions in humans. For customer service, adverse effects reporting, and/or a copy of the SDS, call 1-800-211-3573. . This way, youll lessen the amount of deworming stress they undergo. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. For a better experience, please enable JavaScript in your browser before proceeding. The control group received non-medicated drinking water. Be careful to avoid any accidental spill or loss of 1 to 1 dilution which may inadvertently result in less than the required dose of fenbendazole. Proprietary, innovative wet-milling technique produces highly stable suspension in drinking water. Stir until the content in the stock suspension tank is visibly homogeneous. Safe-Guard AquaSol was administered orally as medicated drinking water to a group of 110 breeding chickens (10 male and 100 female) at 3 mg fenbendazole/kg body weight/day (3 times the recommended label dose) for 21 consecutive days (4 times the recommended duration). The aquasol is formulated to be mixed in water, so it will stay suspended correctly. if(typeof ez_ad_units != 'undefined'){ez_ad_units.push([[300,250],'farmandchill_com-leader-2','ezslot_16',106,'0','0'])};__ez_fad_position('div-gpt-ad-farmandchill_com-leader-2-0'); According toMerck Animal Health, the manufacturer of Safe-Guard Aquasol, there is no egg withdrawal period required when using the product as a treatment for chickens. Fenbendazole is a non-FDA approved, off label . At the end of the treatment phase, gross necropsies were performed on 12 hens from each group, and organs weights were evaluated. Chickens: Two margin of safety studies (growing broiler chickens and laying hens at peak egg production) and one reproductive safety study (broiler breeder chickens) were conducted. For oral administration via drinking water. For Patent Information: http://www.merck.com/product/patent/home.html. Stir the medicated water in the medication tank until the medicated water is visibly homogeneous. In all chickens, feed and water intake, body weights, clinical health, and mortality were recorded. Palatability: A pivotal palatability study was conducted to evaluate the palatability of 20% Fenbendazole Suspension in pigs through voluntary consumption of medicated water when offered for approximately 5 hours a day over 3 consecutive days at a dose of 2.2mg fenbendazole/kg body weight (BW) per day (label dose). 6) Add the 1 to 1 dilution of Safe-Guard AquaSol in water to the water supply system as described below. Another group of 120 chickens (60 male and 60 female) was provided non-medicated drinking water and used as a control group. There was a significant treatment effect in T. suis worm counts between medicated and non-medicated treatment groups at each study site (p=0.0006 in MN and p=0.0003 in CA). Each mL of Safe-Guard AquaSol contains 200 mg of fenbendazole. Barrow and gilt breeds representative of U.S. commercial production were used. Swine: Safe-Guard AquaSol must be administered orally to swine via the drinking water at a daily dose of 2.2 mg/kg BW (1 mg/lb) for 3 consecutive days. Zhejiang Apeloa Kangyu Pharmaceutical Co., Ltd. In the study, the efficacy against adult A. galli and H. gallinarum was 98.7% and 99.2%, respectively. No further stirring during administration is necessary. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. The parameters evaluated in the study included feed and water intake, body weights, clinical health, egg production and weight, fertility, hatchability, and 14-day old chick viability. if(typeof ez_ad_units != 'undefined'){ez_ad_units.push([[250,250],'farmandchill_com-large-mobile-banner-2','ezslot_12',107,'0','0'])};__ez_fad_position('div-gpt-ad-farmandchill_com-large-mobile-banner-2-0'); Safe-Guard Aquasol requires oral administration to chickens by mixing it with their water first before letting them consume it. Histopathologic examinations were performed on 12 hens each from the control and 5 mg fenbendazole/kg body weight groups. So Safeguard it is. Safe-Guard AquaSol was administered orally as medicated drinking water to three groups of 120chickens (60male and 60 female in each group) at 1, 3, and 5 mg fenbendazole/kg body weight/day (1, 3, and 5 times the recommended label dose) for 15 consecutive days (3 times the recommended duration). It lives freely inside the chicken's small intestine. Adequacy of infection was demonstrated at both study sites by having more than 6 non-medicated pigs (11 of the 12 non-medicated animals in MN and 9 of the 12 non-medicated animals in CA) with adult T. suis worm counts of 100 or more per animal. Safe-Guard AquaSol was administered orally as medicated drinking water to three groups of 120 chickens (60 male and 60 female in each group) at 1, 3, and 5 mg fenbendazole/kg body weight/day (1, 3, and 5 times the recommended label dose) for 15 consecutive days (3 times the recommended duration). Net volume 1 Liter, Set id: 62bd7997-81e5-46ca-806c-7407344449ae. Fenbendazole (active ingred.) Histopathologic examinations were performed on 12 hens each from the control and 5 mg fenbendazole/kg body weight groups. Conventional poultry producers typically administer Fenbendazole to pullets (age 17 weeks of age) or Copyright 2020 Intervet Inc., a subsidiary of Merck & Co., Inc., Madison, NJ 07940. USER SAFETY WARNINGS: Not for use in humans. Safe-Guard AquaSol is indicated for the treatment and control of adult Ascaridia galli in broilerchickens and replacement chickens intended to become breeding chickens and for thetreatment and control of adult A. galli and Heterakis gallinarum in breeding chickens. Sorry, I have searched and searched on here, and I can't find the answer. -> at 20%, this would be 0.00227mL of product/lb, which might be a . All dewormers require accurate dosing for best results. See the Terms of Use for further details. A sixth dose confirmation study was conducted in the US using 176 Ross breed broiler chickens (4 to 5 weeks old). There were no abnormal post-treatment observations attributed to administration of FBZ at either study site. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS, or http://www.fda.gov/AnimalVeterinary/SafetyHealth.
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